Esomeprazole Magnesium (EC) & Domperidone (SR) Pellets

Esomeprazole Magnesium (EC) & Domperidone (SR) Pellets

Esomeprazole+ Domperidone falls under a class of gastrointestinal medicines that are used to cure stomach ulcers, Zollinger-Ellison syndrome, and gastroesophageal reflux disease (GERD). The mucous layer shields the stomach usually from acid. In a few instances, when there is more acid produced in the body than required, it erodes the mucous layer, resulting in complications such as GERD, acidity, stomach ulcers, and Zollinger-Ellison syndrome.

Esomeprazole+ Domperidone is a mixture of Esomeprazole (proton pump inhibitor) and Domperidone (dopamine antagonist) drugs. Esomeprazole inhibits an enzyme known as the gastric proton pump that generates acid. Domperidone inhibits the movements and contractions of stomach muscles. Both Esomeprazole and domperidone, together, assist in treating acidity-related issues.

Benefits:

• Esomeprazole+ Domperidone is prescribed for the treatment of gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and peptic ulcers.
• It can also be used in the management of nausea, vomiting, stomach fullness, belching, severe bloating, heartburn, acidity, gas, pain in the upper abdomen, erosive oesophagitis, and difficulty in swallowing.
• Esomeprazole is a proton pump inhibitor that inhibits an enzyme known as gastric proton pump, which is involved in acid production.
• Domperidone is a dopamine antagonist and acts by raising the movements as well as stomach muscle contractions.

Uses:

• Domperidone + Esomeprazole are applied to manage gastroesophageal reflux disease (acid reflux) and to cure indigestion symptoms like heartburn, stomach discomfort, and inflammation.
• These drugs act synergistically to enhance gastrointestinal health and effectively treat discomfort due to excess stomach acid, giving relief from these all-too-common gastrointestinal complaints.

Directions to use:

• Use these pellets after the consultation with your medical expert.
• Carefully read all the directions before using this drug.
• Administer this medication 30 minutes before eating.
• Do not chew and break these pellets.
• Swallow this with a whole glass of water.

Storage:

Store these pellets in a dry and cool place. Store this medicine out of children’s and pet’s reach. Don’t keep this medicine from direct sunlight.

Dosage:

Take this medicine in a proper dose and at the proper time as suggested by your healthcare professional. Do not exceed the dose of this medicine because it may cause worse effects. To take more benefit of this medicine take this at the same time daily.

Side Effects:

• Dry mouth
• Stomach pain
• Diarrhea
• Headache
• Flatulence
• Constipation
• Vomiting

Precautions:

• You have been prescribed Domperidone + Esomeprazole for acidity and heartburn treatment.
• Take it an hour before eating, ideally in the morning.
• It is a very well-tolerated drug and gives relief for a prolonged period.
• Notify your doctor if you experience watery diarrhea, stomach pain that persists, or fever.
• Notify your doctor if you do not get better after 14 days of taking it because you might be suffering from some other ailment that has to be addressed.
• Use over the long term may lead to brittle bones and mineral deficiencies like magnesium deficiency. Maintain proper dietary calcium and magnesium intake or supplements, as recommended by your physician.

Frequently Asked Questions (FAQ):

Q. When is the best time to take Domperidone+ Esomeprazole?

It should be taken with Domperidone+ Esomeprazole before the morning’s first meal or on an empty stomach.

Q. Can Domperidone+ Esomeprazole use lead to abnormal heartbeat?

Yes, the combination of Domperidone+ Esomeprazole may make irregular heartbeat (serious arrhythmias) more likely. It is a severe side effect but the likelihood of it occurring is extremely low. The risk is possibly a bit higher in patients over 60 years old.

Q. What are the contraindications associated with the use of Domperidone+ Esomeprazole?

The use of Domperidone+ Esomeprazole is thought to be unsafe in patients with a documented hypersensitivity to rabeprazole or domperidone or other inactive ingredients of the drug. Caution is exercised in patients with renal or hepatic disease.