Cinnarizine & Dimenhydrinate Tablets

Cinnarizine 20 mg & Dimenhydrinate 40 mg tablets

Cinnarizine & Dimenhydrinate Tablets are a combination oral medicine for the symptomatic treatment of vertigo. This tablet contains cinnarizine & dimenhydrinate as prescribed by Jamkas Pharma. The product is included in the company’s tablet portfolio and can be supplied for third-party manufacturing requirements.

The combination encompasses two medications (to different parts of the vestibular system). Cinnarizine possesses an important action on vestibular stimulation, whereas the action of dimenhydrinate is mainly directed to the central vestibular system. The same 20/40 combination has a description of indication as vertigo symptoms of various origins in adults in a product monograph.

Composition

Each tablet contains:

Cinnarizine 

Dimenhydrinate 

Therapeutic Category

• Anti-vertigo/Vestibular Suppressant
• The combination is used for the symptomatic treatment of vertigo and associated vestibular symptoms.

Key Uses / Indications

The formulation can be used for:

• Vertigo that has various causes
• Loss of balance related to VSG disorders
• Nausea accompanying vertigo
• Anorexia with dizziness or nausea. Nausea or vomiting and dizziness.
• Symptomatic treatment for vestibular disturbances for short durations. 
• Symptomatic short-term management of the vestibular abnormalities.

Product Benefits

The interaction of these two may provide benefits such as

• Assists in alleviating symptoms of dizziness.
• Helps manage any associated nausea and vomiting.
• Combines peripheral and central vestibular actions.
• Easy to be administered orally.
• May be prescribed for short-term relief of symptoms.
• Formulated as a tablet to be used for pharmaceutical production.

Dosage Form

Tablet

How It Works?

Cinnarizine is mainly effective on the peripheral vestibular system and has the ability to decrease influx of calcium ions into the sensory cells of the vestibular system. On a central level, dimenhydrinate has one predominant action on the vestibular system, which in turn has an effect on the symptoms associated with vertigo.

The combination of these mechanisms can help decrease abnormal vestibular stimulation and alleviate spinning sensation, dizziness, and associated nausea.

Important Precautions

• It should be used as prescribed by a medical practitioner. Patients should avoid driving or machinery operation while taking cinnarizine or dimenhydrinate, as this may cause drowsiness.
• However, drowsiness can be worsened if they also take alcohol or other medications that cause sleepiness. Patients should consult with their doctor before using if they have any of the following disorders: Glaucoma, urinary retention disorders, Respiratory disorders or severe liver or kidney disease.
• According to the product information, there is a risk of severe renal impairment or hepatopathy in patients, who should therefore be avoided in these cases.

Storage

• Keep in a cool and dry place.
• Keep from direct sunlight and water.
• Keep in the original container.
• Avoid giving to children.
• Follow directions given on the Storage Instructions label at the end of the finished product.

Frequently Asked Questions ( FAQ )

What is the use of Cinnarizine & Dimenhydrinate tablets?

They are used for symptomatic treatment of vertigo and any associated vestibular symptoms.

Do these tablets make you sleepy?

Yes. Both can cause dizziness. Advise patients to avoid operating a motor vehicle or machinery.

Do children fit this combination?

Product information cited indicates that there is a lack of data regarding safety and efficacy in children under 18 years of age. Therefore, the use must rely on professional medical advice.

For how long will medication be used?

The length of treatment is determined by the cause. This general information on the products listed usually suggests short-term usage and advises doctors to evaluate medication longer.